Morphologic and immunopathologic findings in myasthenia gravis and in congenital myasthenic syndromes.

A Case Report of Congenital Myasthenia Gravis Presenting With Respiratory Distress

Congenital Myasthenic Syndromes (CMS) are rare inherited disorders characterized by dysfunction of neuromuscular transmission at the neuromuscular junction. Most patients with congenital myasthenic syndromes present in the infancy. Major symptoms of affected individuals include weakness and fatigue during the first years of life. Patients may show hypotonia, facial weakness, swallowing difficul...

Association between myasthenia gravis and HLA antigens in patients

Introduction: Myasthenia gravis is a disease of neuromuscular junction. Familial cases have been reported. Relation between myasthenia gravis and HLA antigens has been seen in many studies from different parts of the world. The aim of this study is determination of association between HLA class I haplotypes and myasthenia gravis in Kerman province. Methods: In this cross sectional study 44 my...

Comparison of Two Different Induction Doses of Atracurium in Myasthenia Gravis in Patients Undergoing Thymectomy

Introduction:yasthenia gravis is an autoimmune disorder resulting from a decreased number of active acetylcholine receptors at the neuromuscular junction. Thymectomy is one of its current treatments. Due to sensitivity of myasthenic patients to non-depolarizing muscle relaxants and also the interaction of this medication with anti-cholinestrase drugs, determining the dosage of non-depolarizing ...

Congenital myasthenic syndromes and myasthenia gravis are challenging diagnoses in neurological practice.

Childhood myasthenia: clinical subtypes and practical management.

In recent years, understanding of the pathogenesis and clinical presentation of distinct myasthenia subtypes has increased significantly. This article reviews the clinical manifestations of autoimmune myasthenia gravis (including myasthenia associated with anti-muscle-specific kinase antibodies), ocular myasthenia, and antibody negative myasthenia. The following treatments are examined: choline...